Aubrey Plaza has collaborated with Cointreau since 2023, starring in multiple campaigns that promote the brand's role in classic cocktails. Notably, she led the 'Make Your Margarita MargaRight' campaign, emphasizing Cointreau as an essential ingredient in Margaritas, and later featured in the 'Keep it Cosmo' campaign, highlighting its importance in the Cosmopolitan cocktail.

Aubrey Plaza reunited with co-star Nick Offerman for a Mountain Dew commercial in February 2024. The ad, created by Goodby, Silverstein and Partners, showcased their comedic chemistry to promote the beverage's Baja Blast.