Karlie Kloss was the face of Topshop's spring/summer 2016 campaign. At 23, she reunited with the brand, marking a significant moment in her modeling career as it came eight years after her first job with them. This campaign highlighted her continued presence in the fashion industry and her lasting relationship with the brand.

Karlie Kloss acquired i-D Magazine from Vice Media Group in November 2023 through her company, Bedford Media. She will serve as CEO, guiding the magazine's future direction. This acquisition marks a significant step in Kloss's career as a model, investor, and entrepreneur.