Simone Biles entered a long-term partnership with Athleta in April 2021, aiming to empower women and girls through a shared vision. This partnership focuses on fostering community and inspiring the next generation, with Biles collaborating on design and engaging with the community to support young athletes.

Simone Biles partnered with Barefoot Wine to offer fans an exclusive contest for a chance to attend the Green Bay vs. Chicago game on November 17. The winner and three friends will enjoy pregame sideline access and watch the game from Barefoot's 'BandWAGon Box' suite, marking a unique collaboration between the wine brand and the gymnast.

Simone Biles joined Religion of Sports as a creative partner and board member in February 2025, where she will help produce and direct projects that focus on the stories of individual athletes. This new role builds on her previous collaborations, including the Netflix series 'Simone Biles Rising' and the Facebook Watch series 'Simone vs Herself.'

Simone Biles launched the Simone Biles Legacy Collection with GK Elite, featuring athlete-designed competitive leotards that gymnasts can customize to celebrate their own legacy. This partnership, extended in May 2021, also supports Biles' Gold Over America Tour.

Simone Biles joined Autograph's Advisory Board in August 2021, launching her first collection of NFTs on August 31st. This collaboration allows Simone Biles to design her own digital collectibles and engage with fans in the evolving world of digital collecting.

Simone Biles joined K18 as a brand ambassador in June 2024, leading the inner-strength campaign. She showcases her hair routine that promotes self-expression without compromising hair health, featuring a national TV commercial and collaboration with her hairstylist to highlight the benefits of K18, especially for textured hair and extensions.