Simone Rocha collaborated with Jean Paul Gaultier to create a haute couture collection, merging Gaultier's iconic design codes with her unique aesthetic. This marked Rocha's first-ever Paris couture collection during couture week.

Simone Rocha partnered with J Brand in 2014 to create a 14-piece monochromatic denim collection in pink, red, and black. The collection combines Rocha's eye for Old World silhouettes with modern design, featuring her signature ruffle details on J Brand's premium denim.

Simone Rocha collaborated with H&M to launch a collection on March 11, 2021, celebrating the 10-year anniversary of her brand. This collection included reworkings of her signature designs such as cloqué dresses, broderie anglaise tiered skirts, and oversized embroidered coats, and marked the first time Rocha designed menswear and childrenswear.