William H. Macy and his wife Felicity Huffman collaborated on a campaign for Renew Life Probiotics. According to the announcement, this marked the first time the couple had worked together on a project in several years.
William H. Macy has been the brand ambassador for Woody Creek Distillers since 2018. He owns a home in Woody Creek, Colorado, where he has an attached farm that supplies potatoes to the distillery. Macy frequently appears in advertisements and press events for the brand. In December 2025, they released the William H. Macy Reserve Straight Rye Whiskey, aged 10 years.
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